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0:14
YouTube
Inherited Cancer Registry (ICARE)
A mutation in MLH1 can increase the risk for certain cancers. Early screening and reg...
A mutation in MLH1 can increase the risk for certain cancers. Early screening and regular checkups are key to staying ahead. To learn more, check out the full National Comprehensive Cancer Network (NCCN) guidelines by creating a FREE account at: https://f.mtr.cool/txyurtgtja https://f.mtr.cool/hnmpojzhxr If you tested positive for MLH1, we’d ...
1 month ago
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👆Watch this video 𝗯𝗲𝗳𝗼𝗿𝗲 𝗜𝗩𝗙 𝗼𝗿 𝗱𝗼𝗻𝗮𝘁𝗶𝗻𝗴 𝘆𝗼𝘂𝗿 𝘀𝗽𝗲𝗿𝗺 𝗳𝗼𝗿 𝗜𝗩𝗙 #genetics #dnasequencing #science
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MLH1 MutL Homolog 1
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YouGottaPractice on Instagram: "Explanation: • A. ❌ CIN – Associated with APC mutations, not MLH1. • B. ✅ MSI – Loss of MLH1 → mismatch repair defect → hallmark of MSI. • C. ❌ CIMP – Involves promoter methylation, can silence MLH1 but MSI is the actual phenotype. • D. ❌ p53 – Late event in adenoma-carcinoma sequence, unrelated to MLH1 loss."
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here’s our story. My dad was diagnosed with colon cancer in his 30s… later stomach, duodenal (s/p Whipple), and now another GI cancer. That’s Lynch syndrome. Lynch syndrome is actually more common than BRCA but most people have never heard of it. It’s mutations in DNA repair genes (MLH1, MSH2, MSH6, PMS2) that raise risks for colon, endometrial, ovarian, gastric, pancreatic, urinary tract, and more. This isn’t just about stats. It’s about my dad. My kids. Families everywhere. Screening saves liv
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Zion Ko Lamm, M.D. (고시온) on Instagram: "It’s Hereditary Cancer Awareness Week so i wanted to share our story. My dad was diagnosed with colon cancer in his early 30s. Since then, he’s had stomach cancer, duodenal cancer (s/p Whipple) and now new GI cancer. That’s what Lynch syndrome looks like. When my brother and I were in our 20s, we decided to get tested together. I’ll never forget finding out during residency that I carry the MLH1 mutation. I was devastated. A genetic counselor helped me
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