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med's go on Instagram: "Kartagener syndrome (a subset of primary ciliary dyskinesia) results from a defect in the dynein arms of microtubules in cilia. Normally, dynein generates sliding forces between microtubule doublets in the 9+2 arrangement, allowing ciliary beating. Without functional dynein, cilia are immotile, leading to recurrent respiratory infections (poor mucociliary clearance), infertility (immotile sperm or dysfunctional fallopian tube cilia), and situs inversus due to impaired emb
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