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  1. Pyroptosis - Wikipedia

    Pyroptosis is a highly inflammatory form of lytic programmed cell death that occurs most frequently upon infection with intracellular pathogens and is likely to form part of the …

  2. Pyroptosis: molecular mechanisms and roles in disease

    Apr 3, 2025 · Pyroptosis is a type of programmed necrosis triggered by the detection of pathogens or endogenous danger signals in the cytosol. Pyroptotic cells exhibit a swollen, …

  3. Pyroptosis in inflammatory diseases and cancer - PMC

    Pyroptosis is a lytic and inflammatory type of programmed cell death that is usually triggered by inflammasomes and executed by gasdermin proteins. The main characteristics of pyroptosis …

  4. Pyroptosis - an overview | ScienceDirect Topics

    Pyroptosis is defined as a distinct form of regulated cell death that plays a crucial role in protecting cells from infection by microbial pathogens, characterized by the rupture of the cell membrane …

  5. Pyroptosis Definition: Mechanism, Function, and Role

    Jul 31, 2025 · Pyroptosis is a specific type of programmed cell death characterized by a highly inflammatory response. It actively promotes inflammation through the release of cellular …

  6. Pyroptosis in development, inflammation and disease - Frontiers

    Sep 16, 2022 · The term pyroptosis, derived from the Greek roots pyro (fire/fever) and ptosis (to-sis, falling), was first proposed by D’Souza et al. in 2001 to define this inflammatory cell death (9).

  7. Pyroptosis in health and disease: mechanisms, regulation and …

    Sep 20, 2024 · Pyroptosis is a type of programmed cell death characterized by cell swelling and osmotic lysis, resulting in cytomembrane rupture and release of immunostimulatory …

  8. Pyroptosis: molecular mechanisms and roles in disease

    This review explores the history of pyroptosis, recent insights into gasdermin activation, the cellular consequences of pore formation, and the physiological roles of pyroptosis.

  9. What is Pyroptosis? A Look at Fiery Cell Death - Biology Insights

    Jul 20, 2025 · Pyroptosis is a type of programmed cell death that is part of the body’s immune response to intracellular pathogens. It is a highly inflammatory process that acts as a cellular …

  10. Pyroptosis, a double-edged sword during pathogen infection: a …

    Jul 1, 2025 · Pyroptosis, a distinctive form of programmed cell death (PCD) characterized by its inflammatory nature, is triggered by the activation of pore-forming proteins known as …