BACKGROUND: Despite the high morbidity and mortality of heart failure with preserved ejection fraction (HFpEF), treatment ...

Sex differences in the risk factors, diagnosis, treatment, and outcomes of patients with cardiovascular disease have been ...

Lymphedema is an incurable disease associated with lymphatic dysfunction that causes tissue swelling and fibrosis. We investigated whether lymphedema could be attenuated by interfering with uPARAP ...

A preservation system, the Organ Care System (OCS; TransMedics) uses normothermic pulsatile perfusion during organ transport for heart transplantation. This system has demonstrated favorable outcomes ...

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Dropsy, described in the 17th century, treated with “cure de dechloruration” (bloodletting, leeching, and lancing) and a predecessor of heart failure (HF), yielded to Harvey’s early descriptions of ...

High-quality mechanistic and clinically relevant science to keep clinicians at the forefront of the latest advancements in the diagnosis and treatment of heart failure ...

Epidemiological and anthropological studies suggest that in isolated societies with diets composed primarily of fruits, vegetables, and nuts, hypertension affects only 1% of the population. In ...

The premier international journal in basic and translational cardiovascular biology and source for the most revolutionary research in the field ...