The receptor tyrosine kinase-like orphan 1 (ROR1) is a transmembrane protein expressed during embryonic development. Moreover, it is highly expressed on the surface of several cancer cell types, ...

Life’s most indispensable molecules are not the serene, unchanging fixtures they might appear to be. Even the proteins that ...

NDA supported by positive Phase II registration study data in Chinese patients; follows Breakthrough Therapy Designation granted in 2023 — — Savolitinib has the potential to become the first selective ...

Activating two somatostatin receptors enhances amyloid beta breakdown and improves memory in models of Alzheimer’s disease.

A research team has developed a next-generation anti-inflammatory protein using AI and supercomputing. The team, led by ...

Using high-speed atomic force microscopy (HS-AFM), the Kanazawa University team led by Mikihiro Shibata filmed the dynamic movements of CaMKII at the single-molecule level. The images revealed that a ...

Research presented by Dr Erik Sahai has shown that early, reversible diversity in tumour cell state can blunt the effect of ...

Celcuity Inc. soared on best-in-class Phase 3 breast cancer data. Click to see why I have a Buy rating on CELC due to data, ...

Tesamorelin is a synthetic 44–amino acid analog of growth hormone–releasing hormone (GHRH) that has attracted attention outside the experimental domain for its potential as a research tool. This ...

Researchers at the Kanazawa University Graduate School of Medical Sciences report in PLOS Pathogens a novel role for the ...

Scientists at St. Jude Children's Research Hospital have characterized a hidden intermediate state at the center of Src kinase function. This hidden state allows the kinase to repeatedly modify its ...

Metabolic reprogramming in the tumor microenvironment shapes immune function and therapy resistance, offering insights into ...