The Leducq Foundation is an international grant-making organisation with a mission to improve human health through international efforts to combat cardiovascular disease and stroke. Professor Ruhrberg ...
Copyright: © 2017 The Authors. Published by Elsevier B.V. Leukocyte domiciled midkine is decisive for collateral endothelial cell proliferation in arteriogenesis ...
Development of atherosclerosis leads to narrowing/blockage of large and medium sized arteries and subsequent restriction of blood supply to downstream tissues. Ischaemic disease, including ischaemic ...
Stimulating collateral arteriogenesis is an attractive therapeutic target for peripheral artery disease (PAD). However, the potency of arteriogenesis-stimulation in animal models has not been matched ...
The blood vessel system forms an intricate network of arteries, veins and capillaries that transports oxygen, nutrients, cells and waste products throughout the body. Accordingly, the vasculature ...
MicroRNAs can repress target genes to regulate cellular function in vivo. The miR-17∼92 cluster is critical for cell cycle control, survival signaling, and angiogenesis, but the individual components ...
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