Gut

CD48 is a novel immune checkpoint on tumour‐associated macrophages in hepatocellular carcinoma

Background Hepatocellular carcinoma (HCC) is a leading cause of cancer mortality with limited therapeutic options. Despite ...
Opinion
GutOpinion

Road to IBD prevention in the Global South: a conceptual framework modelling from non-communicable diseases

IBD is rising worldwide and is now a global disease. With the expanding armamentarium of medical therapies, including biologics and small molecules, there is a decline in hospitalisation rates and IBD ...
Gut

Recovery of HBV-specific B cell function after discontinuation of nucleos(t)ide analogue therapy: new insight and future challenges

In hepatitis B virus (HBV) infection, the capacity to mount a functional virus-specific T-cell response has long been considered the principal, if not the sole, immunological determinant of viral ...
Gut

Proton pump inhibitors use and risk of inflammatory bowel disease in children

A recent randomised controlled trial showed that proton pump inhibitors (PPIs), compared with histamine-2 receptor antagonists (H2RAs), induce greater gut microbiome alterations and oral-to-gut ...
Gut

Role of A2 beta casein in milk-induced eosinophilic oesophagitis: novel in-vivo and in-vitro findings

We read with interest the article by Santacroce about personalised medicine in eosinophilic oesophagitis (EoE) and the ...
gut.bmj

Individualised therapy is more cost-effective than dose intensification in patients with Crohn’s disease who lose response to anti-TNF treatment: a randomised, controlled trial

4 Department of Hepatology and Gastroenterology V, Aarhus Hospital, Aarhus, Denmark 5 Department of Gastroenterology, Hvidovre Hospital, Hvidovre, Denmark 6 Department of Medical Gastroenterology S, ...
gut.bmj

Deep mural injury and perforation after colonic endoscopic mucosal resection: a new classification and analysis of risk factors

Objectives Perforation is the most serious complication associated with endoscopic mucosal resection (EMR). We propose a new classification for the appearance and integrity of the muscularis propria ...
gut.bmj

Decreased gut microbiota diversity, delayed Bacteroidetes colonisation and reduced Th1 responses in infants delivered by Caesarean section

3 Department of Clinical and Experimental Medicine, Division of Pediatrics, Linköping University, Linköping, Sweden 4 Department of Clinical and Experimental Medicine, Division of Inflammation ...
gut.bmj

Guidelines on the management of common bile duct stones (CBDS)

The last 30 years have seen major developments in the management of gallstone-related disease, which in the United States alone costs over 6 billion dollars per annum to treat. Endoscopic retrograde ...
gut.bmj

What to do about the leaky gut

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be ...
gut.bmj

Pancolonic indigo carmine dye spraying for the detection of dysplasia in ulcerative colitis

1 Wolfson Unit for Endoscopy and Department of Gastroenterology, St Mark’s Hospital, Harrow, UK 2 Department of Gastrointestinal Histopathology, St Mark’s Hospital, Harrow, UK Correspondence to: Dr B ...
gut.bmj

Glucagon-like peptide-1 receptor agonist use is associated with a lower risk of major adverse liver-related outcomes: a meta-analysis of observational cohort studies

Background Glucagon-like peptide-1 receptor agonists (GLP-1RAs) have shown promising effects on liver histology in phase 2 trials enrolling patients with metabolic dysfunction-associated steatotic ...