Autoimmune and allergic diseases are complex, multifaceted conditions that continue to challenge clinicians and researchers worldwide. Standard ...

A genetics‑guided small molecule called compound 6 gently turns down an overactive immune pathway (CARD9), offering a more precise, durable, and potentially safer treatment strategy for Crohn’s ...

Susannah Rosen was diagnosed with a KIF1A gene mutation at the age of 2½. Patients diagnosed with severe KIF1A gene mutations may live only into early childhood, while patients with mild symptoms can ...

Deaths from both causes are down, but they still eclipse all other causes, according to new statistics. By Nina Agrawal Despite gains in treatment, cardiovascular disease remains the leading cause of ...

Scientists looking to provide relief for people with inflammatory bowel disease have turned to an unusual source for inspiration: barnacles. Inflammatory bowel disease (IBD), such as Crohn’s disease ...

Kidney disease can cause facial swelling, itchiness, and blisters. Symptoms can depend on the stage of kidney disease. Uremic leontiasis ossea is a rare and severe complication of advanced kidney ...

As a two-star Major General, Luis R. Visot is no stranger to formidable challenges. But living with Ménière’s disease has been among the most difficult battles he’s ever faced. For nearly four decades ...

IgG4-related disease (IgG4-RD) is a chronic inflammatory condition. To treat it, doctors often prescribe corticosteroids to reduce inflammation and lower IgG4 levels. But long-term corticosteroid use ...

Treatment for IgG4-related disease aims to decrease inflammation and reduce or eliminate signs of the disease. Even in people without symptoms, treatment is necessary to prevent irreversible organ ...

This conversation features insights from Dr. Joe Murray, professor of medicine, Division of Gastroenterology and Hepatology, Department of Internal Medicine, and Department of Immunology, The Mayo ...

EDITOR’S NOTE: The podcast Chasing Life With Dr. Sanjay Gupta explores the medical science behind some of life’s mysteries big and small. You can listen to episodes here. The “Shaking Palsy.” Those ...