A new study has revealed how tau – a microtubule-binding protein that is implicated in Alzheimer’s disease – weakens transmission across synapses in the brains of mice When injected into presynaptic ...
Schematic representation of axonal transport vesicles (blue) carrying presynaptic proteins (SV and AZ proteins). Kinesin motor proteins (KIF1A) attach these vesicles and carry them along the axons to ...
A holistic inquiry into how toxic tau impacts synapses provides a new take on the processes that lead to neuronal dysfunction and memory loss in Alzheimer’s disease. A tool, developed in the Tracy lab ...