Enable VBA macros (not recommended; potentially dangerous code can run): Enables macros without any conditions. It's the least secure option and exposes your PC to malicious code.

Although Microsoft Excel is a powerful spreadsheet out of the box, macros make it even more useful. You can create and record macros within the app.

If keyboard shortcuts are not working in Excel first check Macro settings or disable Transition navigation keys and see. More suggestions here.