One person died from their injuries at the scene of the crash on northbound I-25 in Denver and paramedics took four to the hospital, three with serious injuries, police said.

One person was killed and four were taken to the hospital after Denver police say someone drove onto Interstate 25 at the Speer Boulevard exit the wrong way.

Police in Denver are investigating a fatal two-vehicle crash on northbound Interstate 25 involving a wrong-way driver early Sunday morning.