Liver fibrosis is a progressive and potentially reversible condition that results from chronic liver damage, which can be ...

You have full access to this article via your institution. To test whether nuclear cloning could be used to generate transgenic mice with targeted insertions, we integrated a tet-transactivator ...

Rutgers Robert Wood Johnson Medical School and collaborating institutions have found that overnutrition leads to insulin ...

Breakthrough polymer-based therapy shows promise in reversing Huntington's disease symptoms by preventing toxic protein ...

Vitamin D deficiency in early life may contribute to biological processes that raise the risk of autoimmune conditions, ...

To mature them and induce meiosis, Kono's team had to transfer them into an enucleated oocyte from a wild-type mouse. With the haploid genome of the mutant oocyte in hand, they were finally ready ...

For decades, scientists believed that mice used ultrasonic vocalizations (USVs ... not unlike the calls of certain types of birds. However, Eduardo Mercado III—a bioacoustics expert at the University ...

A Wild Mouse roller coaster (also Mad Mouse or Crazy Mouse) is a type of roller coaster characterized by small cars that seat four people or fewer and ride on top of the track, taking tight ...

In the female mouse model with Rett syndrome, this gene impairment went in stages. The researchers called this "the seesaw effect." The authors studied the wild-type expressing cells of mosaic ...

Antibodies show promise as candidates for therapeutics as well as tools for advancing mechanistic studies of the HER family receptors.

These observations open the door to more in-depth investigations looking into a potential mechanistic link between TMEM106b aggregation and pathological processes in neurodegeneration,” Rothstein ...

In this study, researchers used comparative flow cytometry analysis of splenocytes, lymph nodes cells, and tumor infiltrating leucocytes from TUSC2 Knock Out and TUSC2 Wild Type mice. FACS analysis ...