Cornell researchers have uncovered a built-in molecular "gate" that controls the production of the molecule nitric oxide, a crucial signaling molecule throughout biology that in humans helps regulate ...

Modulating miR-21 signaling may work to reduce heart damage in people with pulmonary hypertension (PH), a preclinical study suggests.

Primary immunodeficiencies are genetic disorders that impact on the immune system due to defective function of a variety of genes. Among those molecules are ...

We owe a lot to tissue resident memory T cells (T RM). These specialized immune cells are among the body's first responders to disease. Rather than coursing through the bloodstream-as many T cells ...

New research from the University of St Andrews has discovered a crucial piece in the puzzle of how all animals with a spine—including all mammals, fish, reptiles and amphibians—evolved. In a paper ...

Cell signaling is crucial for cells to communicate and function correctly. Disruptions in these pathways, caused by genetic mutations or environmental factors, can lead to uncontrolled cell growth, ...

The remote control doesn’t trigger the self-destruction of the CAR T cells, but simply prompts them to disengage from their cancerous targets.

A new study shows how an anticancer drug triggers an 'outside in' signal that gets it sucked into a cancer cell. The work reveals a new signaling mechanism that could be exploited for delivering other ...

Ossification of the posterior longitudinal ligament (OPLL) is a progressive spinal disease characterized by ectopic bone formation in the spine, leading to severe neurological symptoms due to spinal ...