To become infectious, HIV has to undergo a maturation process, which involves a rearrangement of the matrix proteins (red). In an immature virus particle, the matrix proteins form a lose lattice ...

portray the structure, dynamics ... A study reports that the structural maturation of the matrix domain of the Gag protein of HIV-1 is induced by the proteolytic release and binding of the ...

Because it only takes nanoseconds to microseconds for a protein to morph along its path to its final structure, the scientists needed to slow down the process during their analysis to be able to catch ...

Another important discovery was an intricate RNA structure near the critical ... to produce the correct proportions of two key proteins, Gag and Gag-Pol, which are necessary for assembling ...

The sequence of amino acids in the chain determines how the chain will fold up to make the protein, so different proteins have different three-dimensional shapes. The three-dimensional shape of a ...

Proteins have four levels of structure: primary (amino acid sequence), secondary (local folding patterns like alpha helices and beta sheets), tertiary (overall 3D shape), and quaternary (assembly of ...

Learn about our Editorial Policies. While AlphaFold and the subsequent AI revolution in biology garnered a lot of attention, the foundational bricks for the strides made in protein structure and ...