Prolonged insufficient physical activity in adulthood increases the body's stress burden, according to a large longitudinal ...

About two millennia ago, the Greek physicians Hippocrates and Galen suggested that melancholia—depression brought on by an excess of "black bile" in the body—contributed to cancer. Since then, scores ...

A long-studied metabolic hormone, FGF21, also acts as a stress hormone—a discovery that helps explain how psychological stress causes metabolic dysregulation and drives physical disease, according to ...

Researchers uncover the mechanism by which ribosomes raise alarms in the cell. Ribosomes, the protein factories of the cell, are essential for all living organisms. They bind to mRNA and move along ...

New research led by Professor Yogesh Dwivedi at the University of Alabama at Birmingham uncovers how long noncoding RNAs engage chromatin-silencing machinery under glucocorticoid receptor activation, ...

Physician and Author of The Stress Paradox: Why You Need Stress to Live Longer, Healthier, and Happier Physician and Author of The Stress Paradox: Why You Need Stress to Live Longer, Healthier, and ...

Redox biology investigates how reversible oxidation–reduction (redox) reactions regulate fundamental cellular processes. Central to this field is the role of reactive oxygen species (ROS), such as ...

In 2019 I wrote about research suggesting anti-inflammatory medications might help some people with major depression. At the time, the idea that depression could have roots in the immune system felt ...