Do SERMs Favorably Impact Clinical Markers of Cardiovascular Risk? In women, menopause is accompanied by clear changes in serum lipoproteins, [30] and plasma lipoprotein levels are clear predictors of ...
Selective estrogen-receptor (ER) modulators (SERMs) are synthetic nonsteroidal compounds that switch on and switch off target sites throughout the body. Tamoxifen, the pioneering SERM, blocks estrogen ...
S-Phase Fraction and Urokinase Plasminogen Activator Are Better Markers for Distant Recurrences Than Nottingham Prognostic Index and Histologic Grade in a Prospective Study of Premenopausal Lymph Node ...
SAN DIEGO and GAINESVILLE, Ga., May 23, 2023 (GLOBE NEWSWIRE) -- Societal CDMO, Inc. (SCTL) (“Societal CDMO”; Nasdaq: SCTL), a contract development and manufacturing organization (CDMO) dedicated to ...
Hormone therapy in older women with breast cancer was associated with a reduced risk of subsequent dementia, a retrospective study of Medicare patients suggested. Breast cancer patients who received ...
The Women’s Health Initiative study in 2002 had a lasting negative effect on the use of menopausal hormone therapy (MHT), which combines estrogen with medroxyprogesterone acetate (MPA). Although the ...
A research paper published today (8 February 2024) in The Lancet Oncology demonstrates that the drug enobosarm, a selective androgen receptor modulator which stimulates the male sex hormone receptor ...
(RTTNews) - Athira Pharma, Inc. (ATHA) has acquired exclusive global rights to Lasofoxifene, a selective estrogen receptor modulator now in pivotal Phase 3 trial for ESR1-mutant metastatic breast ...
Novel lasofoxifene combined with abemaciclib (Verzenio) produced encouraging progression-free survival (PFS) along with acceptable toxicity in pretreated, locally advanced or metastatic breast cancer ...