Intracellular membrane fusion requires not only SNARE proteins but also other regulatory proteins such as the Rab and Sec1/ Munc18 (SM) family proteins. Although neuronal SNARE proteins alone can ...
The two universally required components of the intracellular membrane fusion machinery, SNARE and SM (Sec1/Munc18-like) proteins, play complementary roles in fusion. Vesicular and target ...
The chaperone Hsc70 (green) helps keep SNAP-25 in the proper shape so that it can help form the SNARE complex, enabling neurotransmission. AMHERST, Mass. – A team of researchers from the University of ...
The peptide commonly referred to as SNAP-8 (acetyl octapeptide-3) is a synthetic fragment derivative of SNAP-25, engineered ...
SNARE proteins dock packets, or vesicles, of neurotransmitters such as glutamate on the membrane of neurons so they can be released across the synapse. Tomosyn was also suspected to be a target of an ...
Researchers describe, for the first time, the full molecular cascade that comprises acrosomal exocytosis, an essential step in fertilization, in this week's PLoS Biology. "Exocytosis has been analyzed ...
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