Researchers report the development of a mouse model of Fukuyama's muscular dystrophy that copies the pathology seen in the human form of the disease. Muscular dystrophy is a complicated set of genetic ...

In a new study, researchers demonstrate that affected muscle may directly contribute to inflammation in muscular dystrophy. Dr. Kanneboyina Nagaraju and colleagues at the Children's National Medical ...

The Hidetoshi Sakurai Laboratory at CiRA has successfully reproduced the pathology of Myotonic Dystrophy type 1 (DM1) using skeletal muscle cells generated from patient-derived iPS cells and ...

Philadelphia, PA, January 15, 2013 – A new study has found that tamoxifen, a well-known breast cancer drug, can counteract some pathologic features in a mouse model of Duchenne muscular dystrophy (DMD ...

Scientists in the U.S. have demonstrated that long-term therapy with the selective estrogen receptor modulators (SERMs) tamoxifen and raloxifene helps to slow disease progression in a mouse model of ...

Amsterdam, NL, February, 26. 2015 - The muscular dystrophies are known to target various muscle groups differentially. In addition to making limb muscles weak, muscular dystrophy (MD) can also lead to ...

The muscular dystrophies represent disorders of progressive muscular degeneration and weakness. As a group, they exhibit clinical heterogeneity that reflects diverse molecular mechanisms responsible ...

Facioscapulohumeral muscular dystrophy (FSHD) is a severe muscle disorder caused by aberrant DUX4 mRNA expression in skeletal muscle. DUX4 activates downstream target transcriptome, known as D4T, ...

Recent studies have defined a group of muscular dystrophies, now termed the dystroglycanopathies, as novel disorders of glycosylation. These conditions include Walker–Warburg syndrome, ...

Muscular dystrophy is a group of diseases that make muscles weaker and less flexible over time. It is caused by a problem in the genes that control how the body keeps muscles healthy. For some people, ...