One in three families knows someone living with memory loss, and late-onset Alzheimer’s disease affects tens of millions worldwide. The strongest common genetic risk factor is APOE: the E4 isoform ...

Researchers have reversed memory loss in aging mice by targeting a protein that builds up in brain cells, pointing toward a potential pathway to counter the cognitive declines of aging. In a new study ...

Age-related memory decline and neurodegenerative diseases like Alzheimer's are often thought of as irreversible. But the ...

Memories are thought to be stored in sparse groups of neurons called engrams. These are the cells that switch on during learning and can later switch on again during recall. In physiological aging and ...

Researchers have identified two brain receptors that help the brain clear away amyloid beta, a hallmark of Alzheimer’s ...

A protein called ferritin light chain 1 (FTL1) may play a significant role in brain aging, a new study reveals, giving scientists a new target for understanding and potentially preventing brain ...

A team of researchers at Washington University School of Medicine in St. Louis has found that accelerating the brain’s waste removal system could have tremendous implications for our memory. As ...

Age-related changes in protein tagging and degradation may help explain how the brain declines over time and why diet can still influence these processes.

Researchers at UC San Francisco have identified a biological process that may explain why exercise sharpens thinking and ...

For decades, scientists have looked at various mechanisms responsible for the decline of our mental faculties as we age. A new discovery shows that the accumulation of a certain protein called the ...

A UCSF team finds a liver protein, released with exercise, that improves memory in aging and Alzheimer’s disease by repairing ...