Receptors are specialised membrane‐bound proteins that play a fundamental role in translating extracellular signals into precise intracellular responses. Integral to cellular communication, these ...
Researchers found that mice lacking membrane ERα signaling in osteoblast lineage cells had significantly lower cortical bone mass, highlighting the pathway’s critical role in maintaining the strength ...
The novel biosensor technology used in this study can also be transferred to other so-called G protein-coupled receptors (GPCRs), which act as crucial “signal receivers” in our cells and are of major ...
Kanazawa University, in collaboration with Osaka University and the National Institutes for Quantum Science and Technology, ...
The intricate regulation of receptor tyrosine kinases (RTKs) underpins a vast array of cellular responses that are essential for growth, differentiation and survival. In particular, the interplay ...
A research group consisting of Professor Masahiro Nishibori (Specially Appointed Professor), Department of Translational Research and Drug Development, Faculty of Medicine, Dentistry and ...
Drug discovery is shifting from static snapshots to moving pictures. Instead of inferring how medicines work from end results ...
A genetic mutation passed from mother to children in families affected by schizophrenia has now been shown to completely silence a brain receptor that pharmaceutical companies are racing to target ...