Fluorescence microscopy-based image restoration has received widespread attention in the life sciences and has led to significant progress, benefiting from deep learning technology. However, most ...

In PhotoniX, researchers report a self-supervised deep learning method that denoises dynamic fluorescence images in vivo without requiring clean training data. The figure shows in vivo venule images ...

Volumetric fluorescence microscopy is an indispensable tool for comprehensive studies of cells and organs. Since the specimens are inherently three-dimensional (3D), the optimal imaging system should ...

Fluorescence in Situ Hybridization (FISH) is a technique for macromolecule identification that utilizes the complementarity of DNA or DNA/RNA double strands. Probes, crafted from selected DNA strands ...

In life sciences, confocal fluorescence microscopy (CFM) is widely regarded for producing high-resolution cellular images. However, it requires fluorescent staining, which poses risks of ...

Fluorescence microscopy is a cornerstone of modern biological research, widely used to reveal cellular structures, molecular interactions, and dynamic life processes. Computational fluorescence ...

In recent years, fluorescence quenching microscopy (FQM) 1-3 has emerged as a viable technique that allows for the swift, cost-effective, and accurate imaging of two-dimensional (2D) materials like ...

A new two-photon fluorescence microscope developed at UC Davis can capture high-speed images of neural activity at cellular resolution thanks to a new adaptive sampling scheme and line illumination.

What does the inside of a cell really look like? In the past, standard microscopes were limited in how well they could answer this question. Now, researchers have succeeded in developing a microscope ...