It’s been 22 years since Jamie-Lynn Sigler learned she had multiple sclerosis. In the years since being diagnosed, the former star of “The Sopranos” has taken on a host of projects including roles in ...

It’s raining in the Hollywood Hills outside Christina Applegate’s home as the actress leans her head against Jamie-Lynn Sigler’s shoulder. Gripping Sigler’s hand, Applegate explains that it’s been a ...

In an exclusive clip from their new podcast, MeSsy, Sigler credits Applegate with being "honest and open and vulnerable in a way that took me 22 years to get to" "I wanted to give her tools and things ...

Jamie-Lynn Sigler is detailing a near-death experience she faced during her ongoing battle with multiple sclerosis (MS). On the latest episode of her "MeSsy" podcast with co-host Christina Applegate, ...

The 'Dead to Me' actress has one daughter, Sadie, while 'The Neighbor In The Window' star is a mother to two sons, Jack and Beau Mike Coppola/Getty for Tribeca Festival; Gilbert Flores/Variety via ...