The increased deposition of connective tissue is a problem in chronic diseases of many organs such as the lungs (idiopathic pulmonary fibrosis), liver (cirrhosis), kidneys (kidney fibrosis), gut ...

Connective tissue diseases can be genetic or autoimmune. Symptoms may vary by disease and can include pain and fatigue. Each disease has its own treatment options. Connective tissue holds the cells of ...

Tissue and cell-type identity lie at the core of human physiology and disease. Understanding the genetic underpinnings of complex tissues and individual cell lineages is crucial for developing ...

Figure 1: PPFs contain Gata4 + muscle connective tissue fibroblasts that migrate independently and in advance of myogenic cells. Figure 2: Deletion of Gata4 in the PPFs produces localized amuscular ...

Mixed connective tissue disease (MCTD) is a complex and relatively rare autoimmune disorder. It shares symptoms with lupus, systemic sclerosis, and myositis. MCTD is a challenging condition that can ...

THE relation between the thyroid gland and rheumatic disorders has long excited interest. 1–7 In particular, an association between some of the connective-tissue diseases and Hashimoto's thyroiditis ...

The novel radiotracer ¹⁸F-FAPI-RGD in PET/CT scans shows potential for diagnosing ILD in connective tissue disease patients by highlighting fibroblast activation and tissue remodeling. Patients with ...

A connective tissue protein known to support the framework of organs also encourages immune responses that fight bacterial infections, while restraining responses that can be deadly in the condition ...

Correspondence to Professor Paul William Hodges, Centre of Clinical Research Excellence in Spinal Pain, Injury and Health, School of Health and Rehabilitation Sciences, The University of Queensland, ...

The increased deposition of connective tissue is a problem in chronic diseases of many organs such as the lungs (idiopathic pulmonary fibrosis), liver (cirrhosis), kidneys (kidney fibrosis), gut ...

Scientists from Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Department of Medicine 3 - Rheumatology and Immunology, headed by Prof. Dr. Georg Schett, have now decrypted a molecular ...