Drug discovery is shifting from static snapshots to moving pictures. Instead of inferring how medicines work from end results ...

A research team of the University Medical Center Mainz has succeeded in observing for the first time how G protein-coupled ...

Every time our body encounters a new disease-causing agent, a crucial defense system called adaptive immunity comes into play ...

The novel biosensor technology used in this study can also be transferred to other so-called G protein-coupled receptors (GPCRs), which act as crucial “signal receivers” in our cells and are of major ...

Adhesion G protein-coupled receptors have a large extracellular region (shown in green and orange) that extends into space outside the cell. Almost 35% of drugs approved by the Food and Drug ...

Many people are familiar with histamine, a biological molecule that serves as a key driver of allergic reactions and other ...

Triggering receptors expressed on myeloid cells (TREMs) are a cell surface receptor family found on granulocytes, monocytes, macrophages, and dendritic cells—as well as other myeloid cells in general.

Proteomics experiments on Drosophila reveal sex-specific effects in aging, and an important role for a protein called DIP-β.

Scientists have found that antibodies stop UTI-causing E. coli by jamming or mimicking cell receptors, preventing bacterial ...

A research team led by Dr. Àlex Bayés, Head of the Molecular Physiology of the Synapse Group at the Institut de Recerca Sant Pau (IR Sant Pau), has achieved what for decades had been an elusive goal: ...