The cells lining skin capillaries are constantly sending each other messages—tiny pulses of calcium that help regulate blood ...

Researchers at Texas A&M Health and collaborators have developed engineered CRAC channel inhibitory binders that can ...

Cell signaling is crucial for cells to communicate and function correctly. Disruptions in these pathways, caused by genetic mutations or environmental factors, can lead to uncontrolled cell growth, ...

Regeneration has fascinated humankind for millennia — think of Greek mythology figures such as the giant Tityus (whose liver could regenerate) or the serpent Hydra (that grew two heads for every one ...

The only route for S1P formation is via the phosphorylation of sphingosine at its C1 hydroxyl group by the sphingosine kinases. Two sphingosine kinases exist, SPHK1 and SPHK2. These are intracellular ...

One of the most important mechanisms is receptor-mediated signaling. A peptide attaches to a specific receptor on the cell surface, which then activates intracellular proteins such as kinases or ...

Many types of cancer are caused by gene mutations in the signalling pathways that control cell growth, such as the hedgehog signalling pathway. A new study from the Karolinska Institutet, published in ...

Researchers discover that the GPR3 receptor acts as an immediate-early gene to jumpstart neuron and synapse development.