“Our findings suggest a role for NSD2 in maintaining MM cell identity, with potential implications for future therapeutic strategies based on targeting of NSD2.” “Our findings suggest a role for NSD2 ...

Scientists at City of Hope have uncovered a gene called SMOC1 that plays a surprising role in the development of type 2 diabetes (T2D) by converting pancreatic cells that normally produce insulin into ...

A new research paper was published in Oncotarget, Volume 16, on March 21, 2025, titled "NSD2-epigenomic reprogramming and maintenance of plasma cell phenotype in t(4;14) myeloma." Researchers Andrea ...

The genetic network of BTB zinc finger transcription factors and Eip93F is crucial for Kenyon cell identity regulation and neuronal function acquisition in the construction of Drosophila mushroom ...

The adult mammalian heart bears limited regenerative capacity, resulting in the irreversible loss of cardiomyocytes post-cardiac injury, and often culminating in end-stage heart failure. Cardiomyocyte ...

New research has investigated the mechanism by which bivalency functions to poise genes for expression during cell differentiation, providing insight into a long-standing paradigm in the regulation of ...

How do stem cells know what to become? Nearly three decades after scientists isolated the first human embryonic stem cells, researchers are still working hard to understand precisely how a single, ...

Mitochondrial defects are associated with the development of diseases such as type 2 diabetes (T2D). Studies in mice and in human tissues, by researchers at the University of Michigan, have now found ...

LOS ANGELES — Scientists at City of Hope®, one of the largest and most advanced cancer research and treatment organizations in the U.S., and a leading research center for diabetes and other ...