This is a rare feel-good moment in the antibiotic space. Shionogi manufactures and markets cefiderocol, a beta-lactam antibiotic that utilizes a clever siderophore strategy to enter and kill ...
MALVERN, Pa. & PARSIPPANY, N.J.--(BUSINESS WIRE)--Venatorx Pharmaceuticals (Venatorx) and Melinta Therapeutics (Melinta) announced today that the U.S. Food and Drug Administration (FDA) issued a ...
Resistance to carbapenems among Enterobacterales is primarily achieved by production of carbapenemases, which are enzymes capable of hydrolyzing carbapenem antibiotics and most other beta-lactams and ...
Bacteria can produce enzymes that make them resistant to antibiotics; one example is the TEM beta-lactamase enzyme, which enables bacteria to develop a resistance to beta-lactam antibiotics, such as ...
Crystal structure of the metallo-beta-lactamase protein 5-(pyridine-3-sulfonamido)-1,3-thiazole-4-carboxylic acid (ANT-431) (image by Simon Leiris). Researchers from the lab group of Michael Crowder, ...
Please provide your email address to receive an email when new articles are posted on . Some gram-negative bacilli, or GNB, are inherently resistant to certain antibiotics. Others acquire resistance ...
Basilea Pharmaceutica Ltd, Allschwil (SIX: BSLN), a commercial-stage biopharmaceutical company committed to meeting the needs of patients with severe bacterial and fungal infections, announced today ...
Some MRSA infections could be tackled using widely-available antibiotics, suggests new research from an international collaboration. Some MRSA infections could be tackled using widely-available ...
The Biomedical Advanced Research and Development Authority (BARDA) in the US will support Basilea’s development of a new type of oral antibiotic to treat complicated urinary tract infections (cUTIs).