We were unable to process your request. Please try again later. If you continue to have this issue please contact [email protected]. Studies assessing bronchoscopic lung volume reduction ...

We were unable to process your request. Please try again later. If you continue to have this issue please contact [email protected]. Augmentation therapy increased survival in patients with ...

Alpha-1-antitrypsin is a so-called protease inhibitor, a type of enzyme inhibitor. It is produced in the liver but exerts its effects in the lungs, where it regulates immune cell activity. This ...

Alpha-1-antitrypsin is a protein produced by the liver. The protein gets secreted to the blood stream, where it circulates the body to protect the lungs. However, some people are born with genetic ...

Alpha-1 antitrypsin deficiency, AATD, is an inherited disease affecting the lung, liver, and, rarely, skin. Alpha-1 antitrypsin, AAT, is a protease inhibitor of the proteolytic enzyme elastase.

Chronic obstructive pulmonary disease (COPD) remains highly prevalent among veterans, but the contribution of alpha-1 antitrypsin deficiency (AAT deficiency or AATD) to this patient population remains ...

Alpha-1 antitrypsin deficiency (AATD) is a hereditary condition characterised by the misfolding of the alpha-1 antitrypsin (AAT) protein, resulting in its hepatic accumulation and compromised protease ...

Serum specimens from 93 members of six families and three additional persons in the United States with serum alpha1-antitrypsin deficiency and familial emphysema were studied to define the genetics of ...

Prime Medicine announces promising preclinical results for a novel AATD treatment using advanced Prime Editing technology, aiming for clinical trials by mid-2026. Prime Medicine, Inc. announced the ...

Boosting levels of a deficient protein has clear survival benefits for people with the genetic condition alpha-1 antitrypsin deficiency (AATD), according to new research led by RCSI University of ...

The two most common inherited liver diseases are hemochromatosis and alpha-1 antitrypsin deficiency. Hemochromatosis is a disease in which deposits of iron collect in the liver and other organs. The ...

As part of an international study, researchers at the Max Planck Institute of Biochemistry used spatial proteomics method called Deep Visual Proteomics to analyze liver tissue from German and Danish ...