Phys.org

Iron catalyst drives asymmetric 1,6 addition of aliphatic Grignard reagents to α,β,γ,δ-unsaturated carbonyl compounds

Scientists at the Institute of Science Tokyo (Science Tokyo) have successfully realized the highly selective asymmetric 1,6 addition of aliphatic Grignard reagents to α,β,γ,δ-unsaturated carbonyl ...
Phys.org

Organocatalyst that controls radical reactions for complex and bulky compound synthesis

Organocatalysts consisting of organic compounds without metal elements are receiving much attention as next generation catalysts in the hope of reducing environmental burden and coping with exhaustion ...
C&EN

Adding two functional groups to an aliphatic alcohol in one shot

Aliphatic alcohols are cheap, widely available, and very stable building blocks for chemical synthesis and drug discovery. Now, a team of chemists has found a way to add functional groups to them in ...
C&EN

Strong, aliphatic C–H bonds succumb to direct arylation

While many chemistries have been developed to incite C–H bonds to react, certain types of aliphatics stubbornly resist such transformations. Now, chemists at Princeton University and Merck & Co. have ...
Princeton University

Enhanced Anaerobic Bioremediation for Chlorinated Aliphatic Hydrocarbon Contaminants in Groundwater

Enhanced anaerobic bioremediation (EAB) is the newest technology in our continuously evolving biological treatment for chlorinated solvent contaminated groundwater. Developments in our understanding ...
EurekAlert!

Highly selective asymmetric 1,6-addition of aliphatic Grignard reagents to α,β,γ,δ-unsaturated carbonyl compounds

The reaction utilizes an iron catalyst together with an N-heterocyclic carbene (NHC) ligand, which suppresses unwanted side reactions to promote highly selective nucleophile addition. In organic ...