Magen David Adom reported that two female medics were injured after their car was hit by shrapnel. Fire and Rescue teams responded to an initial call about a rocket impacting a building in Tel Aviv early Saturday morning. Magen David Adom reported that a Mobile Intensive Care Unit was hit by shrapnel in the Tel Aviv area.

Former Olympian Caitlyn Jenner documented an experience in Israeli shelters as Iran launched missile strikes, posting photos from Jerusalem and Tel Aviv.

CNN's Scott Jennings remains, however, as IDF issues evacuation warnings to Tehran and both sides claim casualties and injuries in the hundreds.

The U.S. Embassy in Israel and its consulate will remain closed as shelter-in-place orders continue following nearby Iranian missile strikes, Ambassador Mike Huckabee confirmed on social media. While no injuries were reported, minor damage occurred near the embassy branch in Tel Aviv due to concussions from missile impacts.

The Iranian and Israeli strikes mark the most sustained, direct attacks ever between the two rivals. Three people were killed in Israel and at least 78 in Iran, officials said.